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γ-aminobutyric acid uptake inhibition and anticonvulsant activity of nipecotic acid esters

✍ Scribed by A. Michael Crider; J. D. Wood; Kathryn D. Tschappat; Christine N. Hinko; Karen Seibert

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
541 KB
Volume
73
Category
Article
ISSN
0022-3549

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📜 SIMILAR VOLUMES

Chelation of endogenous membrane calcium
Chelation of endogenous membrane calcium inhibits γ-aminobutyric acid uptake in synaptosomes
✍ R. Tapia; C. Salazar 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 487 KB

In a previous work, we have demonstrated that calcium chelators induce the release of y-aminobutyric acid (GABA) from synaptosomes in a Na+-dependent manner and that this release is blocked by cations such as Mg2+, La3+, and ruthenium red. In the present study, we show that treatment of synaptosomes