Rapid use-dependent down-regulation of γ
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Mitsuru Saito; Hiroki Toyoda; Hajime Sato; Hisayoshi Ishii; Youngnam Kang
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Article
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2009
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John Wiley and Sons
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English
⚖ 525 KB
Rundown is ubiquitously seen in response to repetitive activation of receptor or ion channels as a use-dependent down-regulation through various mechanisms. In contrast to AMPA receptors, g-aminobutyric acid type A receptor (GABA A R) are believed to display no rapid use-dependent down-regulation. W