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β2-Adrenergic receptor regulates Toll-like receptor-4-induced nuclear factor-κB activation through β-arrestin 2

✍ Scribed by Takako Kizaki; Tetsuya Izawa; Takuya Sakurai; Shukoh Haga; Naoyuki Taniguchi; Hisao Tajiri; Kenji Watanabe; Noorbibi K. Day; Kenji Toba; Hideki Ohno


Book ID
108782269
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
395 KB
Volume
124
Category
Article
ISSN
0019-2805

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Acute exposure to lipopolysaccharide (LPS) can cause hypoglycemia and insulin resistance; the underlying mechanisms, however, are unclear. We set out to determine whether insulin resistance is linked to hypoglycemia through Toll-like receptor-4 (TLR4), myeloid differentiation factor 88 (MyD88), and