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β1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

✍ Scribed by Wintermantel, Tim; Schuetz, Gunther; Mueller, Ulrich; Streuli, Charles H; Hynes, Nancy E; Li, Na; Zhang, Yu; Naylor, Matthew J; Schatzmann, Franziska; Maurer, Francisca

Book ID
110031069
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
591 KB
Volume
24
Category
Article
ISSN
0261-4189

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The mechanisms regulating involution of mammary glands after weaning are not clear, but engorgement with milk is a key trigger. Many cell types require to be anchored to an extracellular matrix (ECM) as a prerequisite for survival and this is achieved via intregrins binding to specific motifs and si