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β-Galactosidase as a novel marker of ischaemic injury and a mechanism for viability assessment in liver transplantation

✍ Scribed by S.D. St. Peter; C.J. Imber; I. Lopez; J. McGuire; T. James; R. Taylor; D. Pigott; P.J. Friend


Book ID
117231533
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
68 KB
Volume
33
Category
Article
ISSN
0041-1345

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High mobility group box 1 protein (HMGB1), a cytokine actively secreted by phagocytes and passively released from necrotic cells, is an inflammatory mediator in experimental hepatic ischemia/reperfusion injury. We characterized its expression in human liver transplantation. In 20 patients, in additi