𝔖 Bobbio Scriptorium
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β-Cyclodextrin derivatives (2-HP-β-CD, SBE4-β-CD) decrease the amphiphilicity and membrane perturbing effects of pilocarpine prodrugs

✍ Scribed by Paula Saarinen-Savolainen; Arto Urtti; Pekka Jarho; Tomi Järvinen


Book ID
117628423
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
670 KB
Volume
5
Category
Article
ISSN
0928-0987

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Degradation of NSC-281612 (4-[bis[2-[(me
✍ M. Jumaa; L. Chimilio; S. Chinnaswamy; S. Silchenko; V.J. Stella 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB

NSC-281612 (4-[bis[2-[(methylsulfonyl) oxy]ethyl]amino]-2-methyl-benzaldehyde, 1), is a chemically unstable, poorly water soluble, experimental antineoplastic agent. The saturated solubility in water at 258C was determined as $30 mg/mL. In the pH range 2-11, 1 displayed pH-independent stability (t