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β-catenin/Tcf signaling in squamous differentiation of porcine airway epithelial cells

✍ Scribed by Wenshu Chen; Renliang Wu; Xi Wang

Book ID
107405730
Publisher
Springer-Verlag
Year
2008
Tongue
Chinese
Weight
176 KB
Volume
28
Category
Article
ISSN
0510-9752

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Activated b-catenin/T-cell factor (Tcf) signalling plays a role in human carcinogenesis. We identified the inhibitory effect of nordihydroguaiaretic acid (NDGA) against b-catenin/Tcf signalling in b-catenin activated cells. NDGA inhibited the transcriptional activity of bcatenin/Tcf in HEK293 cells