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β-amyloid Peptides and Enhancement of Vasoconstriction by Endothelin-1

✍ Scribed by FIONA CRAWFORD; ZHIMING SUO; CHUNHONG FANG; MIKE MULLAN


Book ID
111392814
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
142 KB
Volume
826
Category
Article
ISSN
0890-6564

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Several lines of evidence now suggest that aggregation of soluble amyloid P peptide (AD) into a cross P sheet configuration may be an important factor in mediating potential neurotoxicity of AP. Synthetic AP has been shown to self aggregate in vitro. Here, we demonstrate that coincubation of freshly