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β-Amyloid-induced apoptosis of cerebellar granule cells and cortical neurons: exacerbation by selective inhibition of group I metabotropic glutamate receptors

✍ Scribed by J.W Allen; B.A Eldadah; A.I Faden


Book ID
117188299
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
396 KB
Volume
38
Category
Article
ISSN
0028-3908

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✍ Lluïsa Camón; Pilar Vives; Núria de Vera; Emili Martínez 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB 👁 2 views

While it is well documented that the overactivation of ionotropic glutamate receptors leads to seizures and excitotoxic injury, little is known about the role of metabotropic glutamate receptors (mGluRs) in epileptogenesis and neuronal injury. Intracerebroventricular (i.c.v.) infusion of the group I