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β-Amyloid increases cathepsin D levels in hippocampus

✍ Scribed by Keith B Hoffman; Xiaoning Bi; Jane T Pham; Gary Lynch


Book ID
117476767
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
77 KB
Volume
250
Category
Article
ISSN
0304-3940

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## Abstract Elevations in β‐amyloid peptide (Aβ) levels after traumatic brain injury (TBI) may confer risk for developing Alzheimer's disease in head trauma patients. We investigated the effects of simvastatin, a 3‐hydroxy‐3‐methylglutaryl‐CoA reductase inhibitor, on hippocampal Aβ burden in a clin