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β-Amyloid fragment 25–35 selectively decreases complex IV activity in isolated mitochondria

✍ Scribed by Laura Canevari; John B Clark; Timothy E Bates

Book ID: 117111291
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 151 KB
Volume: 457
Category: Article
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(99)01028-5

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## Abstract Huperzine A, a novel __Lycopodium__ alkaloid originally discovered in the Chinese herb Qian Ceng Ta (__Huperzia serrata__), is a reversible, potent, and selective acetylcholinesterase (AChE) inhibitor and has been extensively used for the treatment of Alzheimer's disease (AD) in China.