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β-Aminopeptidases: enzymatic degradation and synthesis of β-amino acid containing peptides and kinetic resolution of β-amino acid amides

✍ Scribed by T. Heck; B. Geueke; D. Seebach; S. Osswald; M.K.J. Ter Wiel; H.P.E. Kohler

Book ID
108218224
Publisher
Elsevier
Year
2009
Tongue
English
Weight
91 KB
Volume
25
Category
Article
ISSN
1871-6784

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Kinetic Resolution of Aliphatic β-Amino
Kinetic Resolution of Aliphatic β-Amino Acid Amides by β-Aminopeptidases
✍ Tobias Heck; Dieter Seebach; Steffen Osswald; Matthijs K. J. ter Wiel; Hans-Pete 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 281 KB 👁 1 views

## Abstract **Access to enantiopure β‐amino acids**: β‐Aminopeptidases are hydrolases that possess the unique ability to cleave N‐terminal β‐amino acids from peptides and amides. Hydrolysis of racemic β‐amino acid amides catalyzed by these enzymes displays enantioselectivity with strong preference