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β-Adrenergic Receptor Gene Polymorphisms and β-Blocker Treatment Outcomes in Hypertension

✍ Scribed by Pacanowski, MA; Gong, Y; Cooper-DeHoff, RM; Schork, NJ; Shriver, MD; Langaee, TY; Pepine, CJ; Johnson, JA

Book ID
109845474
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
239 KB
Volume
84
Category
Article
ISSN
0009-9236

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## Abstract Both β~1~‐ and β2‐adrenergic receptors (β~1~‐ and β~2~‐AR) have important roles in heart function mainly in response to catecholamines. Some specific polymorphisms in the β~1~‐ and β~2~‐AR genes, named ADRB1 and ADRB2, respectively, have been implicated in several cardiovascular and non