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α,γ-Diamino Acids: Asymmetric Synthesis of New Constrained 6-Amino-3-azabicyclo[3.2.1]octane-6-carboxylic Acids

✍ Scribed by Caputo, Francesco; Cattaneo, Cristian; Clerici, Francesca; Gelmi, Maria Luisa; Pellegrino, Sara


Book ID
121292386
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
128 KB
Volume
71
Category
Article
ISSN
0022-3263

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New methodology for the synthesis of enantiopure 3-aza-6,8-dioxa-bicyclo[3.2.1]octane-carboxylic acids belonging to 7-endo-BTAa sub-class of g/d amino acids is described. The novelty is the use of 2,3-O-isopropylidene-erythrose instead of meso-tartaric acid derivative, thus allowing us to perform an