α,β-Dialkylphenethylamines. Alkylation of Phenylacetone
✍ Scribed by Suter, C. M.; Weston, Arthur W.
- Book ID
- 120439784
- Publisher
- American Chemical Society
- Year
- 1942
- Tongue
- English
- Weight
- 455 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
In connection with studies on the total synthesis of the aglycone of erythromycin B, erythronolide B (II), it was of interest to devise a method for the conversion of the cu,@-unsaturated ketone I to II. The ketone I is an especially attractive synthetic intermediate for several reasons including ac
Alkylation of aldehydes, as a rule. requires transformation into intermediates such as enamines, to prevent base-catalysed condensations'. Only recently a direct alkylation with the aid of a phase-transfer catalyst, of aldehydes with a single a-hydrogen atom, was describedL. To our knowledge, the di