𝔖 Bobbio Scriptorium
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α-Thymidin

✍ Scribed by Hoffer, Max


Publisher
Wiley (John Wiley & Sons)
Year
1960
Tongue
English
Weight
277 KB
Volume
93
Category
Article
ISSN
0009-2940

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## Abstract Thymine‐α,α,α‐d~3~ (**4**) was synthesized from perdeuterated methyl iodide and pyrimidine‐lithium. Thymidine‐α,α,α‐d~3~ (**8**) was then synthesized by coupling compound **4** with 1α‐chloro‐2‐deoxy‐3,5‐bis(p‐toluoyl)‐α‐D‐ribofuranosyl chloride in the presence of Friedal‐Crafts catalys