𝔖 Bobbio Scriptorium
✦   LIBER   ✦

α-Synuclein has structural and functional similarities to small heat shock proteins

✍ Scribed by Thomas Doohun Kim; Eunjin Choi; Hyangshuk Rhim; Seung R. Paik; Chul-Hak Yang

Book ID
116289344
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
984 KB
Volume
324
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibition of α-synuclein aggregation by
Inhibition of α-synuclein aggregation by small heat shock proteins
✍ Ilona B. Bruinsma; Kim A. Bruggink; Karsten Kinast; Alexandra A. M. Versleijen; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 846 KB

## Abstract The fibrillization of α‐synuclein (α‐syn) is a key event in the pathogenesis of α‐synucleinopathies. Mutant α‐syn (A53T, A30P, or E46K), each linked to familial Parkinson's disease, has altered aggregation properties, fibril morphologies, and fibrillization kinetics. Besides α‐syn, Lewy