α-Phosphono-δ-lactones from γ-lactones via a rhodium(II)-catalysed Wolff rearrangement

✍ Scribed by Wissam Dayoub; Youssef Diab; Alain Doutheau

• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 73 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)01814-7

✦ Synopsis

o-Trimethylsilyloxy-a-diazo-b-ketophosphonates were prepared in two steps from g-lactones. After exposure to catalytic rhodium(II) in refluxing toluene and further aqueous treatment, they gave rise to a-phosphono-d-lactones in moderate to good yields.