α-phenyl-β-(3,4-dimethoxy)phenethylamines: Novel inhibitors of choline acetyltransferase from Torpedo electric organ

(±)α-phenyl-β-(3,4-dimethoxy)- and (±)α-

(±)α-phenyl-β-(3,4-dimethoxy)- and (±)α-phenyl-β-(3,4-dihydroxy)phenethylamines: Potential probes for nicotinic acetylcholine receptor-ion channel molecule from Torpedo electric organ

✍ Ragab M. Shafik; Raafat Soliman; Soad A. El-Hawash; Samia A. El-Dardiry; Shebl S 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 371 KB

The synthesis of some N-methyl, N-alkyl derivatives of (+/-)alpha-phenyl-beta-(3,4-dimethoxy)- and (+/-)alpha-phenyl-beta-(3,4-dihydroxy)-phenethylamines was achieved. These compounds were shown to bear certain structural features of acetylcholine (ACh), as well as phencyclidine (PCP). The latter wa