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α-Phenyl-n-tert-butyl-nitrone reduces lipopolysaccharide-induced white matter injury in the neonatal rat brain

✍ Scribed by Lir-Wan Fan; Helen J. Mitchell; Lu-Tai Tien; Baoying Zheng; Yi Pang; Philip G. Rhodes; Zhengwei Cai

Publisher
Wiley (John Wiley & Sons)
Year
2008
Tongue
English
Weight
549 KB
Volume
68
Category
Article
ISSN
1932-8451

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α-Phenyl-n-tert-butyl-nitrone attenuates
α-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced brain injury and improves neurological reflexes and early sensorimotor behavioral performance in juvenile rats
✍ Lir-Wan Fan; Ruei-Feng Chen; Helen J. Mitchell; Rick C. S. Lin; Kimberly L. Simp 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 548 KB

## Abstract Our previous study showed that treatment with α‐phenyl‐__n__‐__tert__‐butyl‐nitrone (PBN) after exposure to lipopolysaccharide (LPS) reduced LPS‐induced white matter injury in the neonatal rat brain. The object of the current study was to further examine whether PBN has long‐lasting pro