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α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences

✍ Scribed by Friedman, Richard L.; Stark, George R.


Book ID
109738781
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
399 KB
Volume
314
Category
Article
ISSN
0028-0836

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HLA-A3 and HLA-B7 class-I genes are differentially regulated in human T lymphoma Jurkat cells, at the trancriptional level, the expression of the HLA-B7 gene being selectively increased following a, p or y interferon (IFN) treatment. Using a series of hybrid CAT constructs, associating HLA-A3 and HL