Cooperative α-helix formation of β-lacto
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Nami Hirota; Yuji Goto; Kazuko Mizuno
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Article
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2008
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Cold Spring Harbor Laboratory Press
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English
⚖ 545 KB
Alcohols denature the native state of proteins, and also stabilize the alpha-helical conformation in unfolded proteins and peptides. Among various alcohols, trifluoroethanol (TFE) and hexafluoroisopropanol (HFIP) are often used because of their high potential to induce such effects. However, the rea