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α-Helical Topology Prediction and Generation of Distance Restraints in Membrane Proteins

✍ Scribed by McAllister, Scott R.; Floudas, Christodoulos A.

Book ID
119921957
Publisher
Biophysical Society
Year
2008
Tongue
English
Weight
811 KB
Volume
95
Category
Article
ISSN
0006-3495

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## Abstract Prediction of membrane spanning segments in β‐barrel outer membrane proteins (OMP) and their topology is an important problem in structural and functional genomics. In this work, we propose a method based on radial basis networks for predicting the number of β‐strands in OMPs and identi