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α-Haloenol Acetates: Versatile Reactants for Oxetan-2-one, Azetidin-2-one and Isoxazolidin-5-one Synthesis.

✍ Scribed by Romain Bejot; Siddam Anjaiah; J. R. Falck; Charles Mioskowski


Publisher
John Wiley and Sons
Year
2007
Weight
29 KB
Volume
38
Category
Article
ISSN
0931-7597

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α-Haloenol Acetates: Versatile Reactants
✍ Romain Bejot; Siddam Anjaiah; J. R. Falck; Charles Mioskowski 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 152 KB

## Abstract New ketene equivalents, namely α‐haloenol acetates, are investigated as both nucleophilic and electrophilic reactants in a tandem aldol–lactonization reaction. Diethylaluminum ethoxide proves to be an efficient promoter for the aldol reaction with a wide range of substrates, including i