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α-Glucosidase isoenzymes in normal and acid maltase-deficient human skeletal muscles

✍ Scribed by Fusako Usuki; Shoichi Ishiura; Ikuya Nonaka; Dr. Hideo Sugita

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 565 KB
Volume: 11
Category: Article
ISSN: 0148-639X
DOI: 10.1002/mus.880110413

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## Abstract ## Background Previously, in murine models of acid maltase deficiency (AMD), we demonstrated that intravenous administration of an improved adenovirus (Ad) vector encoding human acid alpha glucosidase (hGAA) resulted in liver transduction, followed by high‐level hepatocyte‐mediated sec