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α-Glucosidase inhibition (acarbose) fails to enhance secretion of glucagon-like peptide 1 (7–36 amide) and to delay gastric emptying in Type 2 diabetic patients

✍ Scribed by K. Hücking; Z. Kostic; C. Pox; R. Ritzel; J. J. Holst; W. Schmiegel; M. A. Nauck

Book ID
110924394
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
253 KB
Volume
22
Category
Article
ISSN
0742-3071

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Prolonged and enhanced secretion of gluc
Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to α-glucosidase inhibition (acarbose) in Type 2 diabetic patients
✍ Seifarth, C.; Bergmann, J.; Holst, J.J.; Ritzel, R.; Schmiegel, W.; Nauck, M.A. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB 👁 1 views

GLP-1, an incretin hormone of the enteroinsular axis with insulinotropic and glucagonostatic activity, is secreted after nutrient ingestion. GLP-1 is mainly produced by intestinal L-cells in the lower gastrointestinal tract (GIT); simple carbohydrates are absorbed in the upper GIT and ␣-glucosidase