α-Fetoprotein in Wiedemann-Beckwith syndrome
✍ Scribed by Luigi Pavanello; Gianfranco Rizzoni; Barbara Andreetta; Graziella Zacchello; Giovanna Largaiolli
- Book ID
- 119461928
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 174 KB
- Volume
- 109
- Category
- Article
- ISSN
- 1097-6833
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The Wiedemann-Beckwith syndrome (WBS) comprises an accumulation of multiple congenital anomalies. Exomphalos, macroglossia and gigantism are considered the most common manifestations, hence the alternative designation EMG-syndrome. The syndrome carries with it an increased risk of developing specifi
## Abstract Beckwith–Wiedemann syndrome (BWS) is a clinically heterogeneous overgrowth syndrome associated with an increased risk for embryonal tumor development. BWS provides an ideal model system to study epigenetic mechanisms. This condition is caused by a variety of genetic or epigenetic altera