## Abstract Vascular endothelial growth factor (VEGF) inhibitors, such as bevacizumab, have improved outcomes in metastatic colorectal cancer (CRC). Recent studies have suggested that VEGF can delay the onset of cellular senescence in human endothelial cells. As VEGF receptors are known to be upreg
✦ LIBER ✦
α-Catulin knockdown induces senescence in cancer cells
✍ Scribed by Fan, L-C; Chiang, W-F; Liang, C-H; Tsai, Y-T; Wong, T-Y; Chen, K-C; Hong, T-M; Chen, Y-L
- Book ID
- 109972749
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 1000 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0950-9232
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## Abstract Earlier studies identified testes‐specific protease 50 (__TSP50__), which encodes a threonine protease, and showed that it was abnormally reactivated in many breast cancer biopsies. Further, it was shown to be negatively regulated by the __p53__ gene. However, little is known about the