α-Anions—VIII : Dithioesters and ketene mercaptals from aliphatic acids and esters

Stereocontrolled synthesis of α,β-unsatu

Stereocontrolled synthesis of α,β-unsaturated carboxylic esters from O-methyl-C,O-bis(trimethylsilyl)ketene acetal and aliphatic aldehydes

✍ Isamu Matsuda; Yusuke lzumi 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 241 KB

R\*,S\*) Selective aldol type reaction of O-methyl-C,O-bis(trimethylsilyl)ketene acetal (,j.) with aldehydes and stereoselective formation of c,B-unsaturated carboxylic esters are attained by the combination of 2-A and Lewis acids. One of the most versatile methods to E selective synthesis of a,$-un