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α and β Human Transforming Growth Factors Stimulate Prostaglandin Production and Bone Resorption in Cultured Mouse Calvaria

✍ Scribed by Armen H. Tashjian, Edward F. Voelkel, Maribeth Lazzaro, Frederick R. Singer, Anita B. Roberts, Rik Derynck, Marjorie E. Winkler and Lawrence Levine

Book ID
123631991
Publisher
National Academy of Sciences
Year
1985
Tongue
English
Weight
641 KB
Volume
82
Category
Article
ISSN
0027-8424

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Transforming growth factor-β stimulates
Transforming growth factor-β stimulates bone resorption in neonatal mouse calvariae by a prostaglandin-unrelated but cell proliferation-dependent pathway
✍ Dr. Ulf H. Lerner 📂 Article 📅 2009 🏛 American Society for Bone and Mineral Research 🌐 English ⚖ 1023 KB

The relationships between bone resorption, prostanoid formation, and cell proliferation in cultured neonatal mouse calvariae stimulated with transforming growth factor-p (TGF-P) have been examined. Bone resorption was assessed by analyzing the mobilization of minerals (45Ca, Ca2+, Pi) and the releas