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α-Alkylation and α-alkylidenation of carbonyl compounds: Lewis acid-promoted phenylthioalkylation of o-silylated enolates

✍ Scribed by Ian Paterson; Ian Fleming


Book ID
104237759
Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
253 KB
Volume
20
Category
Article
ISSN
0040-4039

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O-Silylated enolates in organic synthesi
✍ Ian Paterson; Lee G. Price 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 224 KB

S7.4mmary: The O-silylated enolates of ketones, aldehydes, esters, and lactones can be regiospecifically alkylated by 1,3-dithienium fluoroborate to give the selectivity protected S-dicarbonyl compounds. We have found that the reaction of O-silylated enolates with a-chloroalkyl phenyl sulphides (Ph