## Abstract The hydrazides of both optical isomers of amino acids and isolysergic acid were tested for effects on amine oxidases. There was little action on monoamine oxidase (MO). However, some of the amino acid hydrazides, such as L‐leucylhydrazide, turned out to be very effective inhibitors of d
✦ LIBER ✦
Über die Wirkung von 2-Phenylcyclopropylaminen auf die monoamin-oxydase und andere Enzymsysteme. 18. Mitteilung über Amin-oxydasen
✍ Scribed by Satyapriya Sarkar; Renuka Banerjee; Marian S. Ise; E. Albert Zeller
- Publisher
- John Wiley and Sons
- Year
- 1960
- Tongue
- German
- Weight
- 581 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
- Monoamine oxidase (MO) does not attack cyclopropylamine, cyclohexylamine, cis‐ and trans‐phenylcyclopropylamine. These results are consistent with previous observations that MO is unable to catalyze the degradation of α‐alkylated amines.
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## Abstract The pI~50~‐values of 1,2‐dimethyl‐, 1,2‐diethyl‐ and 1,2‐dipropyl‐hydrazine are of the order 4,7 for monoamine oxidase (MO) and about 5,8 for diamine oxidase (DO). For both enzymes the pI~50~‐values of 1,2‐diisopropylhydrazine are much smaller^30^). Under conditions similar to those of