Über Dibenzo-thiazepin-Derivate und ihre pharmakologische Wirkung

✍ Scribed by R. Jaques; A. Rossi; E. Urech; H. J. Bein; K. Hoffmann

• Publisher: John Wiley and Sons
• Year: 1959
• Tongue: German
• Weight: 702 KB
• Volume: 42
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.19590420422

✦ Synopsis

Abstract

The synthesis and pharmacological activity of basically substituted dibenzothiazepines are described. They possess interesting antihistamine and antiserotonine activity. By varying the substituents in the benzene nuclei, and by a suitable choice the basic side chains, the specifity and activity of some derivatives could be increased considerably, especially with the dibenzothiazepinones.