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Étude Structurale des Analogues de la Minaprine: 1. Structure Moléculaire du Dichlorhydrate de la Desméthylminaprine

✍ Scribed by A. Michel; R. Gustin; G. Evrard; F. Durant

Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
298 KB
Volume
91
Category
Article
ISSN
0037-9646

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✦ Synopsis

Abstract

This paper initiates a series of structural studies on analogs of minaprine, a psychotropic drug, in order to establish structure‐activity relationships. The results of the crystal structure analysis of the desmethylminaprine.2 HCl.H~2~O are related. In particular, we discuss the electronic delocalization in the aminopyridazlnium moiety.

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✍ A. Michel; R. Gustin; G. Evrard; F. Durant 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) ⚖ 225 KB

## Abstract This study is part of a more general investigation about conformations of morpholinoethylamino pyridazines. Some of these molecules exhibit psychotropic activity related with the substitution on the pyridazine ring. The molecular structure of the title compound analyzed by X‐Ray diffra