✦ LIBER ✦
Zur Problematik der Peptidsynthese an Trägern: Beitrag eines neuen Verfahrens mit löslichen Trägern
✍ Scribed by R. H. Andreatta; H. Rink
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- German
- Weight
- 979 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
A new procedure for the synthesis of peptides on a soluble carrier is described. It relies on gel filtration for the removal of low molecular weight reactants from the peptide‐polymer complex after each cycle. The advantages of the method are assessed and the insight into the problematics of the carrier synthesis which it provides are discussed. Finally, the use of a monovalent, soluble carrieer molecule of defined chemistry is proposed. Such a carrier should reduce the problems of carrier synthesis to the purely chemical ones commonly associated with peptide synthesis.