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Zur Kenntnis der sesquiterpenoiden C12-Ketone des ätherischen Öls von Vetiveria zizanioides (L.) Nash

✍ Scribed by B. Maurer; M. Fracheboud; A. Grieder; G. Ohloff


Book ID
102856371
Publisher
John Wiley and Sons
Year
1972
Tongue
German
Weight
766 KB
Volume
55
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Two new C~12~‐ketones, (+)‐(1__S__, 10__R__)‐1,10‐dimethylbicyclo[4.4.0]dec‐6‐en‐3‐one (5) and (+)‐(6__S__, 10__S__)‐6,10‐dimethylbicyclo[4.4.0]dec‐1‐en‐3‐one (6), have been isolated from Reunion vetiver oil (Vetiveria zizanioides (L.) Nash). Structure and absolute configuration of 5 were established by a four‐step synthesis from (+)‐isonootkatone ((+)‐α‐vetivone) (1). The structure of 6 followed from its spectroscopic properties and was confirmed by direct comparison with an authentic racemic sample. The absolute configuration of 6 was established by chemical correlation with (+)‐α‐eudesmol (13).