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ZR-75-1 human breast cancer cells: expression of inducible nitric oxide synthase and effect of tamoxifen and phorbol ester on nitric oxide production

✍ Scribed by O Alalami; J.H.J Martin

Book ID: 117468693
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 570 KB
Volume: 123
Category: Article
ISSN: 0304-3835
DOI: 10.1016/s0304-3835(97)00404-7

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## Abstract A proinflammatory cytokine IFN‐γ stimulates microglia in the injured brain; however, signaling pathways for IFN‐γ‐mediated microglia activation are not well characterized. In the present study, a protein kinase C (PKC) activator phorbol 12‐myristate 13‐acetate (PMA) acts in concert with