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Zone-electrophoretic pattern of proteins in the cystic fluid of ovarian tumors

✍ Scribed by Liselotte Mettler; Christiane Mäder

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
488 KB
Volume
29
Category
Article
ISSN
0008-543X

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✦ Synopsis

Fifty-one ovarian cystomas and cystic ovarian tumors were analyzed by vertical disc-electrophoresis for their protein content and the pattern of their protein distribution. In order to find typical electrophoretic patterns for the different kinds of cystomas, the protein fractions detected were correlated with seven histologically distinct groups. The results were compared with normal human serum pherograms.

OUR PER CENT OF ALL GYNECOLOGIC CASES, F treated surgically, concern ovarian tumors.7 This accounted for 4.5% of all our surgical admissions in the last 12 months. In order to obtain etiologic, as well as diagnostic, data on the biochemical composition of ovarian tumors, we analyzed a broad spectrum of ovarian cystomas and cystic ovarian tumors. In particular, the pattern of proteins, enzymes, lipoproteins, and mucoproteins was considered.

In a careful review of the literature, no information on quantitative analysis of proteins in ovarian tumors was found. Our purpose was to find distinctive patterns of protein fractions which correspond to a certain histologic diagnosis.

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