Zonal distribution of peroxisomal 3-oxoacyl-CoA thiolase mRNA in liver from rats treated with di-(2-ethylhexyl) phthalate

In vivo mutational analysis of liver DNA

In vivo mutational analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3-methylimidazo[4,5-f]quinoline, and di(2-ethylhexyl)phthalate

✍ Keita Kanki; Akiyoshi Nishikawa; Ken-ichi Masumura; Takashi Umemura; Takayoshi I 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 222 KB 👁 1 views

## Abstract In order to cast light on carcinogen‐specific molecular mechanisms underlying experimental hepatocarcinogenesis in rats, in vivo mutagenicity and mutation spectra of known genotoxic rat hepatocarcinogens __N__‐nitrosopyrrolidine (NPYR), and 2‐amino‐3‐methylimidazo[4,5‐__f__]quinoline (I