Zona Pellucida and Progesterone-Induced Ca2+ Signaling and Acrosome Reaction in Human Spermatozoa
β Scribed by JACKSON C. KIRKMAN-BROWN; EMMA L. PUNT; CHRISTOPHER L. R. BARRATT; STEPHEN J. PUBLICOVER
- Book ID
- 118761115
- Publisher
- American Society of Andrology
- Year
- 2002
- Tongue
- English
- Weight
- 214 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1939-4640
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## Abstract Spermatozoa from the spermβrich fractions of the semen of 6 beagle dogs were capacitated and the effect of both zona pellucida (ZP) proteins and progesterone on calcium flux and the acrosome reaction measured. Sperm calcium flux was determined using the dual wavelength calcium probe ind
## Abstract We investigated, using guineaβpig spermatozoa as a model, whether phospholipase A~2~ (PLA~2~) is involved in progesterone or zona pellucida (ZP)βstimulated acrosomal exocytosis, if progesterone enhances ZPβinduced activation of PLA~2~, and mechanisms underlying PLA~2~ regulation. Sperma