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Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases : A double-blind, randomized dose–response study

✍ Scribed by James R. Berenson; Lee S. Rosen; Anthony Howell; Lester Porter; Robert E. Coleman; Walter Morley; Robert Dreicer; Steven A. Kuross; Allan Lipton; John J. Seaman


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
118 KB
Volume
91
Category
Article
ISSN
0008-543X

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## Abstract ## BACKGROUND The goal of the current study was to compare the long‐term (25‐month) safety and efficacy of zoledronic acid with pamidronate in patients with bone lesions secondary to advanced breast carcinoma or multiple myeloma. ## METHODS Patients (__n__ = 1648) were randomized to