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Zoledronic acid induces apoptosis and changes the TRAIL/OPG ratio in breast cancer cells

✍ Scribed by Tilman D. Rachner; Shiv K. Singh; Michael Schoppet; Peggy Benad; Martin Bornhäuser; Volker Ellenrieder; Regina Ebert; Franz Jakob; Lorenz C. Hofbauer

Book ID
116335289
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
720 KB
Volume
287
Category
Article
ISSN
0304-3835

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## Abstract We investigated whether the combination of zoledronic acid and doxorubicin induced apoptosis of breast and prostate cancer cell lines, and if synergistic interaction was present. We investigated whether the levels of cell death altered depending on the sequence in which the drugs were a