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ZnO nanorods catalyzedN-alkylation of piperidin-4-one, 4(3H)-pyrimidone, and ethyl 6-chloro-1,2-dihydro-2-oxo-4-phenylquinoline-3-carboxylate

✍ Scribed by Selvaraj Mohana Roopan; Fazlur Rahman Nawaz Khan

Book ID: 111491380
Publisher: Versita
Year: 2010
Tongue: English
Weight: 231 KB
Volume: 64
Category: Article
ISSN: 0366-6352
DOI: 10.2478/s11696-010-0045-3

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✦ Synopsis

Abstract

An efficient ligand-free cross-coupling reaction of 2-chloro-3-(chloromethyl)benzo[h]quinoline with N-heterocycles such as piperidin-4-one, 4(3H)-pyrimidone, and ethyl 6-chloro-1,2-dihydro-2-oxo-4-phenylquinoline-3-carboxylate using a catalytic amount of ZnO nanorods as a recyclable catalyst and KOH as the base in DMSO under reflux at 110°C is reported.

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