Inhibition of proliferation and inductio
β
Manuela Campiglio; Alberta Locatelli; Clelia Olgiati; Nicola Normanno; Giulia So
π
Article
π
2003
π
John Wiley and Sons
π
English
β 297 KB
π 2 views
High expression of the epidermal growth factor receptor (EGFR) in breast carcinoma confers a growth advantage to the tumor cells. The EGFR tyrosine kinase inhibitor (EGFR-TKI) ZD1839 ('Iressa') has clinical activity in a wide range of tumor types, although the mechanism(s) by which it exerts its ant