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Zirconium-Mediated SN2′ Substitution of Allylic Ethers: Regio- and Stereospecific Formation of Protected Allylic Amines.

✍ Scribed by Gojko Lalic; Suzanne A. Blum; Robert G. Bergman


Publisher
John Wiley and Sons
Year
2006
Weight
29 KB
Volume
37
Category
Article
ISSN
0931-7597

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✍ José Barluenga; Félix Rodríguez; Lucía Álvarez-Rodrigo; José M. Zapico; Francisc 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 183 KB

## Abstract An easy and efficient zirconium‐mediated synthesis of allylamines from simple amines and enol ethers is described. This strategy also allows the synthesis of amino alcohol derivatives containing a __Z__ double bond in their structure when 2,3‐dihydrofuran is used. Simple conventional mo