Zirconium and hafnium cations rapidly cleave model phosphodiesters in acidic aqueous solutions

✍ Scribed by Robert A. Moss; Jing Zhang; Kaliappa G. Ragunathan

• Book ID: 104258866
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 209 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00074-4

✦ Synopsis

Aqueous solutions of 20-fold excess Zr 4+ and Hf ~+ at pH 3.5 (37 °C) hydrolyze phosphodiester substrates 1-3 very rapidly. The reactivity of Zr 4+ (with rate constants up to 0.015 s 1 for 2 at 1 mM Zr 4+) exceeds that of most other transition metal cations.