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Zinc prevents the copper-induced damage of cultured astrocytes

✍ Scribed by Ivo F. Scheiber; Maike M. Schmidt; Ralf Dringen

Book ID
116765518
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
937 KB
Volume
57
Category
Article
ISSN
0197-0186

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## Abstract Transient global ischemia induces CA1 hippocampal neuronal death without astrocyte death, perhaps mediated in part by the toxic translocation of zinc from presynaptic terminals to postsynaptic neurons. We tested the hypothesis that cellular depolarization, which occurs in the ischemic b