Zinc-mediated attenuation of hippocampal mossy fiber long-term potentiation induced by forskolin
β Scribed by Masaki Ando; Naoto Oku; Atsushi Takeda
- Book ID
- 116765536
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 342 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0197-0186
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## Abstract The role of zinc in longβterm potentiation (LTP) at hippocampal mossy fiber synapses is controversial because of the contrary results obtained when using zinc chelators. On the basis of the postulation that exogenous zinc enhances the action of zinc released from mossy fibers, mossy fib
Much of the current interest in the hippocampus concerns a rapid and persistent form of synaptic plasticity, called long-term potentiation (LTP), that is a candidate substrate for some of the mnemonic functions of this structure. There are at least two kinds of LTP in the hippocampus. One form is fo