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Zidovudine transport within the rabbit brain during intracerebroventricular administration and the effect of probenecid

✍ Scribed by Yanfeng Wang; Yuxian Wei; Ronald J. Sawchuk

Book ID
109388430
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
253 KB
Volume
86
Category
Article
ISSN
0022-3549

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πŸ“œ SIMILAR VOLUMES

Zidovudine transport in the rabbit brain
Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion
✍ Yanfeng Wang; Ronald J. Sawchuk πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 790 KB

The distribution of zidovudine (AZT) between plasma, brain extracellular fluid (ECF), and cerebrospinal fluid (CSF) was investigated in a crossover design study (n = 5) in unanesthetized rabbits. Drug was administered by intravenous (iv) and intracerebroventricular (icv) infusions at the same infusi