Zidovudine Overdose in an Asymptomatic HIV Seropositive Patient With Hemophilia
β Scribed by Stern, Robert A.; van der Horst, Charles M.; Hooper, Stephen R.; Bloodgood, Karen M.; High, Katherine A.
- Book ID
- 121780127
- Publisher
- American Psychiatric Publishing Inc
- Year
- 1992
- Tongue
- English
- Weight
- 479 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1545-7206
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This paper reports the results of the cross-sectional phase of a long-term follow-up investigation, carried out on a sample representative of the broad population of HIV-1 infected patients, with the objective of evaluating the possible neurocognitive effects of zidovudine and 2', 3'-dideoxyinosine,
During a randomized double-blind study to assess the antiviral activity of saquinavir (SQV) alone or in combination with zidovudine (ZDV), the emergence of phenotypic resistance was evaluated in 44 patients treated with SQV (13 subjects), ZDV (14 subjects), and SQV plus ZDV (17 subjects). A signific